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Showing posts from March, 2016

Review on Kadamba plant

Review on Kadamba : Description of the plant: Kadamba Biological Source: Drug consists of dried stem bark of Anthocephalus chinensis(Lamk.) A. Rich. ex Walp. (Plate ) (Syn. A. cadamba (Roxb.) Miq.; A. indicus A.  Rich.); Family: Rubiaceae Distribution: It is a large deciduous tree, found all over India in moist, warm, deciduous and evergreen forests. Other Names Assam. - Roghu, Kadam Beng. - Kadam Guj. - Kadamb, Kadam Hind. - Kadam, Kadamb Kan. - Kadamba, Kadamba mara, Kadavala A large tree, branches spreading, bark dark-brown. Leaves simple, opposite, entire,caducous,coriaceous, stipules lanceolate. Inflorescence  globose, penduncled solitary head; flowers orange colored with white stigma, scented at night. Fruit confluent into a fleshy globose mass. yellow or orange-colored, scented flowers; fruit a fleshy, orange, globose pseudocorp of compressed angular capsules with persistent calyx; seeds small, muriculate. Anthocephalus cadamba family Rubiaceae amedium sized t

Pathophysiology of Hyperlipidemia

Pathophysiology of Hyperlipidemia  An understanding of the biology of the lipoproteins and the pathophysiology of hyperlipidemic states is essential to the rational choice of treatment regimen. • Exogenous pathway: Route of uptake of dietary lipids: Chylomicrons (CM) are complexes of triglycerides (TG), cholesteryl esters (CE), and apoproteins. After the removal of triglycerides they become chylomicron remnants . Chylomicrons are degraded by lipoprotein lipase on endothelial cells of adipose tissue and muscle. After removal of TG for storage, the CM remnants are transported to the liver. This results in dietary TG stored in adipose tissue  and muscles. • Endogenous pathway: Route for distribution of cholesteryl esters (CE) from liver to target cells :VLDL is secreted by the liver into plasma and transported to adipose tissue and muscles, where lipoprotein lipase extracts most triglycerides. The  remnant IDL is either taken up by the liver or circulated until the remaining 

Key Enzyme of Lipid Formation

 Lipid is formed by  Two convergent pathways for triacylglycerol biosynthesis. The stepwise acylation of glycerol through the two pathways for triacylglycerol synthesis are shown. Abbreviations: fatty acid (FA), glycerol-3-phosphate (G-3-P), G-3-P acyltransferase (GPAT), lysophosphatidic acid (LPA), acylglycerol-3-phosphate acyltransferase (AGPAT), phosphatidic acid (PA), monoacylglycerol (MAG), MAG acyltransferase (MGAT), diacylglycerol (DAG), DAG acyltransferase (DGAT), and triacylglycerol (TAG). Acyl-CoA: monoacylglycerol acyltransferase (MGAT)  Acyl-CoA: monoacylglycerol acyltransferase (MGAT) catalyzes the synthesis of  diacylglycerols from monoacylglycerols and long chain fatty acyl-CoAs, a first step  in the monoacylglycerol pathway that is major route of triacylglycerol synthesis. This   pathway contributes more than 80% of glycerolipid synthesis in the intestinal mucosa. MGAT isoforms and expression MGAT 1 Mouse MGAT-1, identified by its sequence homology to acyl

Vacany in Goverment jobs for various position

Job as Pharmacists (5 posts) in NHM - Govt Job .     Applications are invited for various post like pharmacist, Assistant medical officer, staff nurse, Lab Technician, Psychologist,Optometrist, DentalTechnician  of National Health mission, District Bastar, Chattisgarh. Detail about Pharmacist post:  Post: Pharmacist (RBSK). No.of post: 05. ST: 04, OBC:01. Eucational Qualification: Degree  or  Diploma  in  Pharmacy (50%)  &  Registration  in Pharmacy  Registration  council. Consolidate Salary: 10,000/- Per Month. Age: 18 - 64 years (as on 1 January, 2016) Detail about Asst. Medical Officer Post: Post: AMO (RBSK). No.of post: RBSK. (Male) 06 (Female) 04 ST: 04, OBC:01 Eucational Qualification: BHMS/BAMS/BUMS Degree Registration From any GOI Recognized (BAMS/BHMSA4UMS) Ayush Homeo, Unani Registration Board. OR BDS with registration in Chhattisgarh Medical Council. Consolidate Salary: 20,000/- Per Month. Detail about St

Opportunity for the Post of Manager for B.Pharm & M.Pharm at Government job

Great opportunity for B.Pharm&M.Pharmacy, i need Government jobs At GMSCL,Gandhinagar. For the post of Manager in various areas of field, Experience candidates required and candidates should be registeredv in Gujarat pharmacy council. More details about experience and qualifications of candidates are given below : Gujarat Medical Services Corporation Limited Gandhinagar  invites application for following posts on contractual basis for a Period of 11 months. Applications along with attested copies of educational certificates, certificate in proof of age, experience certificates. Application sent through speed post only by  11/04/2016  at  18:30pm Post:  Manager No. of Posts: Manager (Drug, Procurement) - 01 Manager (Equipment, Procurement) - 01 Manager (Equipment, Maintenance) - 01 Manager (Legal) - 01 Manager (Audit) - 01 Manager (M.I.S) - 01 Remuneration:  Rs.30,000/- Per month (Fixed Pay) Qualification: M.Pharm degree with 3 years of experience in pharma

Opportunity for Freshers in Indian Government as Pharmacist, Nurse, Technician & Specialist (pediatric, radiology, ENT)

Opportunity  for freshers in Indian government. For various post like Jr. Pharmacist, staff nurse, lab technician, doctors ,dietitian more.... ... SAIL, a Maharatna Company, and a leading steel-making company in India with a turnover of 49350 crores (FY 2012-13) is in the process of modernizing and expanding its production units, raw material resources and other facilities to maintain its dominant position in the Indian steel market. Bokaro Steel Plant, one of the modernised integrated steel plants of SAIL employing a motivated workforce of around 18000 employees is producer of HR Coils/Sheets/Plates, CR Coils/ Sheets, GP Sheets/Coils. Bokaro Steel is working towards becoming a one-stop-shop for world-class flat steel in India. SAIL, Bokaro Steel Plant invites online applications from energetic, dynamic medical professionals as Consultant/Specialists for its Bokaro General Hospital , which is a prestigious 910 bed hospital with state of the art equipment, recognised by NB

Opening in Novartis

Opportunity for Pharm.D. and B.Pharm  There is  Recruitment in Novartis  For the Post of Pharmacovigilance. A global healthcare leader Today   Novartis has one of the most exciting product pipelines in the industry. A pipeline of innovative medicines brought to life by diverse, talented & performance driven people. All of which makes them one of the most rewarding employers in their field. Post :  Pharmacovigilance Expert Job work Details  Provide support to the Brand Safety Leader/Pharmacovigilance Leader (PVL/BSL) in monitoring the safety profile of assigned products by providing quality deliverables within agreed timeframes and adhering to a high standard of accuracy in compliance with IMS business rules, standard operating procedures and global and local regulatory requirements. 1. Assist the BSL/PVL in monitoring the safety profile of products potentially including activities such as literature review, evaluation of individual cases or signal detect

Zika Virus Symptoms, Diagnosis & Treatment

Zika Virus  Zika virus disease (Zika) is a disease which is caused by Zika virus that is spread to people primarily by the bite of an infected Aedes species mosquito. The most common symptoms of Zika are fever , rash, joint pain, and conjunctivitis (red eyes). Symptoms, Diagnosis, & Treatment Recommend on Facebook Tweet Symptoms Most of the people infected with Zika virus won’t even know they have the disease because they won’t have symptoms. The most common symptoms of Zika are fever, rash, joint pain, or conjunctivitis (red eyes). Other common symptoms include muscle pain and headache. The incubation period (the time from exposure to symptoms) for Zika virus disease is not known, but is likely to be a few days to a week. See your healthcare provider if you are pregnant and develop a fever, rash, joint pain, or red eyes within 2 weeks after traveling to a place where Zika has been reported. Be sure to tell your health care provider where you t

Opening in MNC Pharmaceutical Freshers & Experience

Walk in interview - MACLEODS As post Officer,  Senior Officers in different departments  Macleods, India’s fastest growing pharmaceutical company, with manufacturing sites approved by USFOA & WHO Geneva, ranked among the top pharmaceutical companies with strength of 10,000 employees, operating 60 countries worldwide, required talented professionals for Formulation Plant at Baddi (HP), Sikkim & Sarlgam. Designation :  Officer, Senior Officer Department -Quality Control  Fresher/ Officer/Sr.Officers - Quality Control Qualification: B.Sc/ M.Sc/B.Pharm/M.Pharm Experience: 0-6 years - Raw Material, Finished Product & Stability, with experience on Analytical Instrumentation - HPLC, GC, and UV IR Department - Production  Fresher/Officer/Sr.Officers - Production/Packing Qualification: B.Pharma/M. Pharma Experience: 0-8 years (Granulation/compression/coating) Strip/blister, Bulk packing. Technical Associate- Production /Packing  Qualification: I